Guitars are supposed to be played - that is a given - but it also means that they will suffer quite a bit of wear and tear, no matter how careful or gentle you are.
The frets and the board itself are the parts which take most of the beating.
Obviously, the frets are under constant friction from the strings. All that grinding can leave the frets in pretty rough shape after a while, especially with a lot of bending and vibrato. You may start feeling like there is sand or something under the strings, making playing very uncomfortable. You can solve that by polishing the frets with a very fine steel wool. It's a good idea to protect the board with tape before starting.